American Airlines’ flight cancellation penalties depend on the ticket type. Non-refundable tickets typically incur a fee, starting at $200 for domestic flights, with the remaining balance credited as a voucher. Refundable tickets and cancellations due to extenuating circumstances often avoid penalties.

https://www.devex.com/people/what-is-the-penalty-for-cancelling-a-flight-on-american-airlines-2096563